EXIA2: Web Server of Accurate and Rapid Protein Catalytic Residue Prediction
Table 1
Comparison of prediction performance of EXIA2 web server and competing method using both sequence and structure information.
Benchmark datasets
PW79
POOL160
EF fold
EF superfamily
EF family
Competing method1
Recall (R)
46.0
78.1
64.2
67.3
61.7
Precision (P)
28.0
19.0
17.1
16.9
18.5
AUCROC
0.963
0.948
—
—
—
EXIA2 + PSSM2
Recall at equal P
63.3
77.8
71.0
70.4
64.3
Precision at equal R
36.5
18.7
19.4
17.7
19.6
AUCROC
0.973
0.965
0.968
0.968
0.968
EXIA23
Recall at equal P
48.8
68.6
43.8
46.9
42.2
Precision at equal R
30.5
14.5
12.0
11.6
12.9
AUCROC
0.962
0.960
0.943
0.944
0.946
Prediction results of Cilia and Passerini [36].
2Prediction results of EXIA2 combined with PSI-Blast PSSM.
3Prediction results of EXIA2 without evolutionary information.
