Evaluation of Cytotoxic and Antimicrobial Effects of Two Bt Cry Proteins on a GMO Safety Perspective

Table 1

Cytotoxic activity of Cry8Ka5 and Cry1Ac proteins on human peripheral lymphocytes evaluated by MTT assay [3-(4,5-dimethylthiazol-2-yl)-2,5-difeniltetrazol] after 72 h exposure.

Proteins	IC50^a  for human lymphocytes (𝜇g/mL)
Cry8Ka5	>1,000
Cry1Ac	>1,000

aConcentration able to inhibit 50% of human lymphocytes growth.