IL-6, IL-8, and IL-10 Are Associated with Hyperferritinemia in Rapidly Progressive Interstitial Lung Disease with Polymyositis/Dermatomyositis

Figure 1

Comparison of the levels of serum ferritin and cytokines in the non-ILD subset, the chronic ILD subset, and the RP-ILD subset. We divided the 38 enrolled patients into three subsets: a non-complication of ILD (non-ILD) subset (𝑛=17), a chronic ILD subset (𝑛=11), and a RP-ILD subset (𝑛=10). Statistical analyses were performed using the Mann-Whitney 𝑈-test for comparisons of median values. 𝑃 values are as indicated below. ^∗<0.05, ^∗∗<0.01, and ^∗∗∗<0.001. The median levels (ranges) of IL-6, IL-8, and IL-10 were 0 pg/mL (0–1.3), 1.7 pg/mL (0.9–6.0), and 0 pg/mL (0-0), respectively, in the 15 healthy controls.