Research Article

A Genome-Wide Identification of Genes Undergoing Recombination and Positive Selection in Neisseria

Table 2

Association between COGs and descriptive variables.

Functional category Number of genes analyzed Bonferroni-corrected value for one-sided test for association between genes in a given COG and(1)
>nt diversity>Number of Informative sites>Codon bias(2)<Codon bias(2)>dS>dN

Energy production and conversion85<0.001
Nucleotide metabolism and transport370.03
Translation, ribosomal structure, and biogenesis110<0.0010.03
Replication, recombination, and repair70<0.001<0.0010.03
Cell wall/membrane/envelope biogenesis750.002
Function unknown930.023 0.03
Intracellular trafficking, secretion and vesicular transport290.020 0.039
Not in COGs470.040 <0.001

“>” or “<” indicates the direction of the one-sided tests (i.e. “>Codon bias” shows Bonferroni-corrected -values for associations between genes in a given COG and higher codon bias as compared to the genes in other COGs, and “<Codon bias” represents a contrast tendency).
Tests for codon bias were performed using Nc values (a lower Nc means increased codon bias).