Recent Developments in Topical Wound Therapy: Impact of Antimicrobiological Changes and Rebalancing the Wound Milieu

Table 1

Overview of the presented wound therapies with classification of the level of innovation.

	Substance	State of the art (Germany)	Innovation level	Importance of the therapy	Hospital/out-patient use	Costs
Autolytic debridement	Wound dressing	Routine	Generic	+++	Both	+/++
Sharp mechanic debridement	Medical device	Routine	Break through	+++	Hospital	+
Mechanical debridement with Debrisoft	Medical device	Selected	Add on	+	Both	++
Growth factors	Drug	Selected	Break through	+	Hospital	+++
Electrospun scaffolds	Drug-device combination	Early development	Break through	+++	Hospital	+++
Silk based wound dressings	Drug-device combination	Early development	Generic	++	Hospital	+++
Platelet-rich fibrin	Drug	Selected	Add on	+	Hospital	+++
Protease inhibitor	Wound dressing	Selected	Break through	++	Both	++
Antiseptics in general	Drug/wound dressing	Routine	Break through	+++	Both	+/++
Silver	Wound dressing	Selected	Break through	++	Both	++
Cold argon plasma	Medical device	Selected	Break through	+++	Hospital	+++
Wound diagnostics: protease levels	Medical device	Selected	At the moment: add-on	++/+++	Hospital	++
Wound diagnostics: pH-values	Medical device	Selected	At the moment: add-on	++/+++	Hospital	+/++