Abarema cochliacarpos Extract Decreases the Inflammatory Process and Skeletal Muscle Injury Induced by Bothrops leucurus Venom
Figure 1
Effect of A. cochliacarpos extract (EAc) on B. leucurus venom’s edematogenic activity. Mice received perimuscular injection of PSS or B. leucurus venom (1 mg/kg). The animals were treated with oral EAc at 100 mg/kg, 200 mg/kg, and 400 mg/kg and i.v. dexamethasone (2 mg/kg) 5 min after venom injection. Results show hind limb edema measured with a caliper rule until 90 minutes after venom injection (panel (a)). Panel (b) shows the area under the curve analysis with the data observed in (a). Data report means ± SEM (). versus venom group (Student’s -test).
