Research Article

Intraoperative Assessment of Surgical Margins of Oral Squamous Cell Carcinoma Using Frozen Sections: A Practical Clinicopathological Management for Recurrences

Table 1

Clinicopathological summary and recurrence status of 236 cases of oral epithelial lesions.

Clinicopathological parametersClinical outcomesP-value for 
difference between 
relapse-free and 
relapse groups
Relapse-free ( )Relapse ( )
Number of casesRatio ( )Number of casesRatio ( )

Sex
 Male11560.21840.00.019
 Female7639.82760.0

Location
 Tongue7740.31431.10.308
 Gingiva7740.32248.90.317
 Buccal mucosa2211.5715.60.454
 Floor of the mouth157.924.40.537

Histopathological diagnosis of main focus
 Squamous cell carcinoma (SCC)12062.83577.80.080
  T130 15.7 7 15.6 0.655
  T241 21.5 12 26.7 1.000
  T38 4.1 5 11.1 0.171
  T441 21.5 11 24.4 0.841
 Carcinoma in situ (CIS)4423613.40.223
 Epithelial dysplasia, moderate115.824.41.000
 Epithelial dysplasia, mild168.424.40.538

Intraoperative assessment of surgical margins by frozen sections
 Yes12867.08354.60.025
 No6333.06945.4