Intraoperative Assessment of Surgical Margins of Oral Squamous Cell Carcinoma Using Frozen Sections: A Practical Clinicopathological Management for Recurrences

Table 4

Histopathology of surgical margins where malignant lesions recurred.

Histopathological diagnosis of margins by previous surgeries	Numbers (%) of recurrent lesions and intervals (month) until recurrences
	Epithelial dyspl asia							CIS			SCC			Total
	Mild			Moderate
	Number	(%)	Period	Number	(%)	Period	Number	(%)	Period	Number	(%)	Period	Number	(%)	Period
Normal/hyperplastic epithelia	0	(0.0)	0.0	0	(0.0)	0.0	1	(50.0)	12.0	1	(50.0)	43.0	2	(100.0)	27.5
Epithelial dysplasia	1	(3.2)	11.0	5	(16.1)	28.4	8	(25.8)	41.8	17	(54.9)	26.1	31	(100.0)	30.0
Mild	0	(0.0)	0.0	2	(22.2)	18.5	2	(22.2)	39.0	5	(55.6)	8.8	9	(100.0)	17.7
Moderate	1	(4.6)	11.0	3	(13.6)	35.0	6	(27.3)	42.7	12	(54.5)	33.3	22	(100.0)	35.0
CIS	0	(0.0)	0.0	0	(0.0)	0.0	15	(42.9)	14.1	20	(57.1)	25.1	35	(100.0)	20.4
SCC	1	(6.2)	2.0	0	(0.0)	0.0	3	(18.8)	12.3	12	(75.0)	22.5	16	(100.0)	19.3
Total	2	(2.4)	6.5	5	(6.0)	28.4	27	(32.1)	22.0	50	(59.5)	25.1	84	(100.0)	23.9