Different Resting-State Functional Connectivity Alterations in Smokers and Nonsmokers with Internet Gaming Addiction

Figure 2

Significant between-group differences in rsFC of different brain regions with PCC between smokers with IGA and HC subjects. Compared with the HC group, the smokers with IGA exhibited increased rsFC in the bilateral cerebellum posterior lobe, bilateral caudate, and left medial frontal cortex. And decreased rsFC were found in the bilateral middle temporal gyrus, bilateral superior parietal lobules, left posterior cerebellum lobe, and right lingual gyrus (, AlphaSim-corrected). The -score bars are shown on the right. Red indicates smokers with IGA > HC and blue indicates smokers with IGA < HC. Note: the left part of the figure (L) represents the participant’s left side; (R) represents the participant’s right side. rsFC: resting-state functional connectivity; HC: healthy control; PCC: posterior cingulate cortex.