Clinical Study
Evaluation of the Efficacy of 50% Autologous Serum Eye Drops in Different Ocular Surface Pathologies
Table 3
Summary of the distribution and evolution of the clinical signs in the 2 groups of patients.
| | Signs | Presence of sign PRE-AS gr 1 | Presence of sign POST-AS gr 1 | Distribution of grades | Distribution of grades |
Average of the
grades PRE-AS
GR.1 |
Average of the
grades POST-AS
GR.1 | P
value |
| | Epithelial defect |
100% |
0% | GRADE 3: 73% | GRADE 3: 0% | |
1 |
<0.01 | | GRADE 2: 27% | GRADE 2: 0% | | GRADE 1: 0% | GRADE 1: 100% |
| | Inflammation |
100% |
14% | GRADE 3: 73% | GRADE 3: 0% | | | <0.01 | | GRADE 2: 27% | GRADE 2: 13% | | GRADE 1: 0% | GRADE 1: 87% |
| | Corneal opacity |
100% |
27% | GRADE 3: 84% | GRADE 3: 0% | | | <0.01 | | GRADE 2: 6% | GRADE 2: 40% | | GRADE 1: 0% | GRADE 1: 60% |
| | Neovascularization |
60% |
40% | GRADE 3: 33% | GRADE 3: 0% | | | <0.01 | | GRADE 2: 27% | GRADE 2: 27% | | GRADE 1: 40% | GRADE 1: 73% | | Epithelial defect |
100% |
0% | GRADE 3: 73% | GRADE 3: 0% | |
1 | <0.01 | | GRADE 2: 27% | GRADE 2: 0% | | GRADE 1: 0% | GRADE 1: 100% |
| | Inflammation |
100% |
10% | GRADE 3: 64% | GRADE 3: 0% | | | <0.01 | | GRADE 2: 36% | GRADE 2: 19% | | GRADE 1: 0% | GRADE 1: 81% |
| | Corneal opacity |
88% |
28% | GRADE 3: 45% | GRADE 3: 0% | | | <0.01 | | GRADE 2: 36% | GRADE 2: 45% | | GRADE 1: 19% | GRADE 1: 55% |
| | Neovascularization |
55% |
45% | GRADE 3: 36% | GRADE 3: 0% | | | <0.01 | | GRADE 2: 18% | GRADE 2: 27% | | GRADE 1: 46% | GRADE 1: 73% |
|
|
Post-AS = postautologous serum treatment; pre-AS = preautologous serum treatment.
|
