Tumor and Endothelial Cell Hybrids Participate in Glioblastoma Vasculature
Figure 3
A subset of glioblastoma stem cells acquires an endothelial phenotype. (a) When GSC-GFP were cocultured with human endothelial cells, several multinucleated and cobblestone GSC-GFP expressing CD31, CD105, VE-cadherin, and vWF were observed (b). The percentage of GSC-GFP expressing CD31 and VE-cadherin obtained in coculture with HUVEC, HUAEC, and hCMEC is indicated for GSC-1, GSC-2, and GSC-3.
