Overexpression of Wnt5a Promotes Angiogenesis in NSCLC

Figure 4

The expressions of some related proteins in NSCLC (immunohistochemical staining, ×200). In Wnt5a-positive group, positive expressions of VE-cadherin, MMP2, and MMP9 were all located in the cytoplasm of tumor cells. However, these proteins were negatively expressed in NSCLC tissues of Wnt5a-negative group. VE-cadherin positive expression in endothelial cells or MMPs positive expression in stromal cells could provide an internal positive control for both, respectively.