Overexpression of Wnt5a Promotes Angiogenesis in NSCLC

Table 2

Relationship between Wnt5a and angiogenesis, expression of related proteins, and β-catenin nuclear expression in NSCLC.

Variant	Total	Wnt5a		P value	𝑟
	𝑛	Negative (%)	Positive (%)
CD34-MVD
<28	92	52 (56.52)	40 (43.48)	0.026	0.157
≥28	113	46 (40.71)	67 (59.29)
VM
Negative	177	73 (41.24)	104 (58.76)	0.021	0.165
Positive	28	5 (17.86)	23 (82.14)
VE-cadherin
Negative	104	50 (48.08)	54 (51.92)	0.004	0.210
Positive	101	28 (27.72)	73 (72.28)
MMP2
Negative	138	65 (47.10)	73 (52.90)	<0.001	0.268
Positive	67	13 (19.40)	54 (80.60)
MMP9
Negative	125	58 (46.40)	67 (53.60)	0.003	0.215
Positive	80	20 (25.00)	60 (75.00)
β-Catenin nuclear expression
Negative	173	72 (41.62)	101 (58.38)	0.017	0.171
Positive	32	6 (18.75)	26 (81.25)

𝑃<0.05 means statistical significance.