Research Article

In Vitro Antiplasmodial Activities and Synergistic Combinations of Differential Solvent Extracts of the Polyherbal Product, Nefang

Figure 1

Isobolograms of the in vitro interactions between differential solvent extracts of Nefang at variable potency ratios. (a): Control CQ/CQ; (b): Control ART/CQ; (c): Cp/Og-EtOH; (d): MiB/Pg-Aq; (e): MiB/Cs- Aq; (f): Cp/Cs-Aq. CQ: Chloroquine; ART: Artemisinin; FIC50 = Fractional Inhibitory Concentration 50. A concave isobologram is consistent with synergy, a convex one is consistent with antagonism, and a straight line is consistent with additivity. Axes are EC50s normalized to 1.
835013.fig.001a
(a) CQ/CQ
835013.fig.001b
(b) ART/CQ
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(c) Cp/Og-EtOH
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(d) MiB/Pg-Aq
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(e) MiB/Cs-Aq
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(f) Cp/Cs-Aq