Outer Electrospun Polycaprolactone Shell Induces Massive Foreign Body Reaction and Impairs Axonal Regeneration through 3D Multichannel Chitosan Nerve Guides
Figure 6
Functional evaluation of nerve regeneration. (a)–(c) Results of the pain perception test (pinch-test) performed weekly on toe III (a), toe IV (b), and toe V (c) are shown. Bars depict the percentage of animals per group with a positive pinch reaction: *intergroup difference to ANT; intergroup difference to COM graft; #intragroup difference to previous week; . (d) Results of the hind limb motor function evaluation by calculation of the static sciatic index (SSI) are presented: significant intragroup improvement in comparison to 4 weeks postsurgery value; ono longer significantly different to presurgery value; .