Human Umbilical Cord Perivascular Cells Exhibited Enhanced Migration Capacity towards Hepatocellular Carcinoma in Comparison with Bone Marrow Mesenchymal Stromal Cells: A Role for Autocrine Motility Factor Receptor
HUCPVCs showed enhanced migration towards AMF in comparison with BM-MSCs. (a) In vitro migration of BM-MSCs (black bars) or HUCPVCs (grey bars) towards rAMF. versus DMEM (0 μg/mL rAMF); versus BM-MSCs. (b) In vitro migration of BM-MSCs (black bars) or HUCPVCs (grey bars) towards HC-PT-5 TCM preincubated with anti-AMF antibody (AMF-ab) or control isotype (IgG-ab) was evaluated. versus IgG-ab; versus BM-MSCs. Bars represent the average of MSCs/field (10x) ± SEM from three representative visual fields. Results are representative of 3 independent experiments.
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