[6]-Shogaol Inhibits α-MSH-Induced Melanogenesis through the Acceleration of ERK and PI3K/Akt-Mediated MITF Degradation

Figure 5

Immunofluorescence analysis. B16F10 cells were treated with [6]-shogaol and fixed at the indicated time and subjected to immunofluorescence detection of MITF protein. DAPI staining was used to illustrate the nuclei. Immunolocalization of MITF in B16F10 cells. The results from three independent experiments are presented. Bars: 10 μm.

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