Formulation and Evaluation of Thermosensitive Biogels for Nose to Brain Delivery of Doxepin

Table 1

Gelation characteristics and pH of drug loaded C-GP and C-GP-PEG systems.

Formulation	Concentration of chitosan; (% w/v)	Concentration of GP (% w/w)	Concentration of PEG (% w/w)	Gelation temperature (°C)	Gelation time; (min)	pH
C-GP-Dox	2	10	—	37.4	7.32	6.93
C-GP-PEG-Dox	2	4.5	1	37	7	6.5