Figure 1: The nucleotide composition (G+C) and ENC, ENCp for the 3047 DENV1–4 genomes tested. (a) Total GC and GC content at the three codon positions for each genome. (b) ENC and ENCp for each genome. The dashed lines in both figures indicate the geographical separation within a DENV serotype. The abbreviations mean the following: AF, Africa; AS, Asia; NA, North America; SA, South America; OC, Oceania.