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BioMed Research International
Volume 2014, Article ID 851425, 9 pages
Research Article

Large-Scale Genomic Analysis of Codon Usage in Dengue Virus and Evaluation of Its Phylogenetic Dependence

1Laboratory of Molecular Biomedicine, Center of Biotechnology on Genomics, National Polytechnic Institute, Colonia Narciso Mendoza, 88710 Reynosa, TAMPS, Mexico
2Laboratory for Cellular Immunology and Immunopathogenesis, Department of Immunology, National School for Biological Sciences (ENCB), National Polytechnic Institute, 11340 New Mexico, DF, Mexico
3Laboratory for Biomedicine, Department of Virology, National School of Medicine and Homeopathy, National Polytechnic Institute, 11340 New Mexico, DF, Mexico

Received 25 February 2014; Revised 5 June 2014; Accepted 11 June 2014; Published 17 July 2014

Academic Editor: Sankar Subramanian

Copyright © 2014 Edgar E. Lara-Ramírez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The accession numbers in NCBI database of genomes tested were provided and the datasets of DENV1–4 genomes for codon usage analysis were shown in an individual excel file. In addition, some statistic results obtained from the analyses were presented in Tables S1–S6. The hierarchical clustering trees based on RSCU data and the phylogenetic trees based on the genome nucleotide sequences were shown in Figure S1.

  1. Supplementary Material