Clinical Correlates of Hachinski Ischemic Score and Vascular Factors in Cognitive Function of Elderly
Table 4
Relationship between HIS and cognitive function and HIS and vascular factors in two groups divided by HIS score.
HIS 0~2 ()
HIS 3~12 ()
P value
Age, yr (mean ± SD)*
73.92 ± 5.40
74.31 ± 5.72
0.388
Male (%)†
63 (29.0)
49 (37.4)
0.105
Family history of dementia (%)†
6 (2.8)
13 (9.9)
0.004
Family history of stroke (%)†
37 (17.1)
31 (23.7)
0.132
Diabetes mellitus (%)†
34 (15.7)
17 (13.0)
0.492
Hypertension (%)†
73 (33.6)
54 (41.2)
0.155
Hyperlipidemia (%)†
11 (5.1)
7 (5.3)
0.911
Cardiac disease (%)†
25 (11.5)
29 (22.1)
0.008
Stroke (%)†
5 (2.3)
15 (11.5)
<0.001
K-MMSE, mean ± SD*
23.59 ± 4.42
22.43 ± 5.13
0.025
CDR, mean ± SD*
0.20 ± 0.26
0.29 ± 0.31
0.008
CDR-SB, mean ± SD*
0.43 ± 0.68
0.79 ± 1.37
0.006
BMI, mean ± SD*
22.73 ± 3.31
23.10 ± 2.98
0.246
HIS: Hachinski ischemic score; SD: standard deviation; K-MMSE, Korean version of Mini-Mental State Examination; CDR, Clinical Dementia Rating; SB, Sum of Boxes; BMI, body mass index. *statistically significant with by independent -test and †Chi-square test.