Comparison of Quasispecies Diversity of HCV between Chronic Hepatitis C and Hepatocellular Carcinoma by Ultradeep Pyrosequencing

Figure 5

Receiver operating characteristic (ROC) curves of 8 nucleotide positions and 14 amino acid positions. (a) ROC curves of 8 nucleotide positions showing significantly different diversities between the patients with chronic hepatitis C and those with hepatocellular carcinoma caused by HCV infection. (b) ROC curves of 14 amino acid positions showing significantly different diversities between the patients with chronic hepatitis C without liver cirrhosis and those with hepatocellular carcinoma caused by HCV infection. AUC: area under the curve.