BioMed Research International / 2014 / Article / Fig 5

Research Article

A RXR Ligand 6-OH-11-O-Hydroxyphenanthrene with Antitumour Properties Enhances (−)-Epigallocatechin-3-gallate Activity in Three Human Breast Carcinoma Cell Lines

Figure 5

Foxo3a immunolocalization and expression in MCF-7, MCF-7TAM, and MDA-MB-231 cells. (a) Immunofluorescence localization of Foxo3a: Foxo3a was found in the nucleus after EGCG+IIF treatments in all the cell lines, especially in MCF-7TAM cells. ; . (b) Foxo3a RT-PCR: Foxo3a expression increased after short time treatments (4 h) in MCF-7 and MCF-7TAM cells and at a later time (24 h) in MDA-MB-231 cells. ; . n.d.: not detected as significant.

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