Anatomic Changes in the Macroscopic Morphology and Microarchitecture of Denervated Long Bone Tissue after Spinal Cord Injury in Rats

Figure 7

Microstructural changes in the femur and tibia at day 33 after unloading because of SCI and reloading by weight bearing (SCI + PS) and artificial muscle contraction (SCI + ES). Acute SCI increased bone resorption (asterisks) in both the tibia and the femur but was remarkably ameliorated by PS. (SCI: spinal cord injury; PS: passive standing; ES: electrical stimulation). Images were captured with an augment of 50x, whence the growth plate was used as the anatomical landmark for the superior limit of the image.