Early Stages of we/we wal/wal Mouse Hair Morphogenesis: Light and Fluorescent Microscopy of the Whole-Mount Epidermis
Figure 2
Distance measurements on 3D images of E18.5 epidermis whole-mount (Keyence VHS-1000). (a) Control C57Bl6 epidermis; ×1500. (b) Mutant epidermis; ×1500. (c) Graphical plot demonstrating average distance between neighboring follicles. Results are presented as mean ± SEM with the level of significance . The distance between two neighboring follicles of any size is significantly increased in mutants in comparison with C57Bl6 embryos, as indicated by the asterisk. Green point: the tip of the follicle, green box: cross section of the hair follicle; the distance between two green points is the distance between follicles, μm. Hair follicle: HF. Basal layer: BL.
