Research Article

Early Stages of we/we wal/wal Mouse Hair Morphogenesis: Light and Fluorescent Microscopy of the Whole-Mount Epidermis

Figure 3

General view of E18.5 epidermis whole-mount. ((a), (b)) Fluorescent microscopy, green—P-cadherin staining. (a) Control C57Bl6 epidermis. (b) Mutant epidermis. (c) Average hair follicles score counted on the standard areas of fluorescent preparations. Results are presented as mean ± SEM with the level of significance . The number of follicles in mutant embryos is significantly decreased in comparison with C57Bl6 mice, as indicated by the asterisk. Early stage is shown by the thick arrow, medium stage is shown by the short arrow, and advanced stage is shown by the long arrow.
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