Moderate Intra-Abdominal Hypertension Leads to Anaerobic Metabolism in the Rectus Abdominis Muscle Tissue of Critically Ill Patients: A Prospective Observational Study
Table 3
Parameters from different studies. Microdialysis catheter was either in RAM tissue (both Maddison et al. studies [7]) or in peritoneal cavity (Hörer et al. [19]).
Parameter
Patient group
Baseline/at inclusion
During/max values
At the end of study
IAP (mmHg)
Elective surgery
Normal(1)
12-13(1)
IAH, decompressed
16 (CI 12–20)(2)
19 (CI 12–23)(2)
IAH, nondecompressed
15 (CI 11–18)(2)
14 (CI 7–15)(2)
ICU
14.5 (12.5–17.8)*
9.8 (9.3–14.9)*
L/P ratio
Elective surgery
10.3 (7.1–15.5)(1)
20.2 (13.1–45.5)(1)
IAH, decompressed
20 (CI 17–25)(2)
24 (CI 17–36)(2)
IAH, nondecompressed
12 (CI 11–16)(2)
13 (CI 10–19)(2)
ICU
49 (36–54)*
24 (22–40)*
Glucose (mM)
Elective surgery
3.3 (0.1–4.4)(1)
0.9 (0.1–4.4)(1)
IAH, decompressed
11.0 (8.0–14.1)(2)
10.0 (6.4–13.6)(2)
IAH, nondecompressed
8.7 (6.1–11.3)(2)
8.9 (CI 6.0–12.5)(2)
ICU
4.1 (3.2–6.5)*
4.4 (3.0–6.3)*
Lactate (mM)
Elective surgery
1.1 (0.3–1.7)(1)#
1.7 (1.2–2.9)(1)#
IAH, decompressed
10.1 (4.8–12.4)(2)
6.5 (3.7–11.2)(2)
IAH, nondecompressed
2.7 (1.7–3.4)(2)
2.6 (CI 1.6–4.2)(2)
ICU
4.7 (2.7–10)*
3.4 (2.3–4.6)*
Pyruvate (M)
Elective surgery
85 (40–125)(1)#
112 (61–175)(1)#
ICU
129 (57–189)*
134 (75–167)*
Glycerol (M)
Elective surgery
103 (65–169)(1)
326 (144–730)(1)
IAH, decompressed
274.6 (172.5–475.4)(2)
245.5 (117.8–512.9)(2)
IAH, non-decompressed
121.7 (62.4–212.7)(2)
135 (CI 76.2–272.9)(2)
ICU
251 (173–408)*
330 (174–361)*
Maddison et al. 2012 [7], 6 patients RAM microdialysis (MD) during elective laparoscopic surgery; #part of the data unpublished. Hörer et al. 2013 [19], 15 patients Intraperitoneal MD during endovascular repair of RAA, non-decompressed (9) and decompressed (6) patients. Current study, 10 ICU patients with IAH.
