Adrenomedullin Deficiency and Aging Exacerbate Ischemic White Matter Injury after Prolonged Cerebral Hypoperfusion in Mice
pCREB expression after prolonged cerebral hypoperfusion in aged groups. (a) Photomicrographs of pCREB staining in the corpus callosum before BCAS (pre) and at day 28. Scale bars = 20 μm. (b) Numbers of pCREB-positive cells in the corpus callosum before BCAS (pre) and at day 28. Data are mean ± SEM of five mice in each group. , , compared with the same time points. Pre: preoperation.
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