Phytochemical Screening, Physicochemical Properties, Acute Toxicity Testing and Screening of Hypoglycaemic Activity of Extracts of Eremurus himalaicus Baker in Normoglycaemic Wistar Strain Albino Rats
Table 4
Effect of different extracts of Eremurus himalaicus on fasting blood glucose levels of normoglycaemic rats.
Groups
Blood glucose level (mg/dL)
0th day
7th day
14th day
% Variation
Normal control
84.01 ± 4.64
82.21 ± 5.58
80.29 ± 6.53
4.43
Ethyl acetate extract, 500 mg/kg
85.00 ± 4.23
82.10 ± 4.60
79.73 ± 4.99
6.20
Ethyl acetate extract, 250 mg/kg
85.14 ± 4.05
84.10 ± 5.14
81.57 ± 6.69
4.22
Aq. extract, 500 mg/kg
81.64 ± 3.72
72.5 ± 3.44
65.58 ± 2.86*
19.67
Aq. extract, 250 mg/kg
81.40 ± 4.08
73.36 ± 2.67
68.51 ± 2.92*
15.83
MeOH extract, 500 mg/kg
81.53 ± 2.38
77.26 ± 1.65
72.74 ± 2.15**
10.78
MeOH extract, 250 mg/kg
84.35 ± 6.21
79.30 ± 4.03
76.08 ± 2.37
9.80
Glibenclamide, 10 mg/kg
84.22 ± 2.26
71.59 ± 2.41*
65.36 ± 3.80*
22.39
Data represented as mean ± S.D values of 6 animals each. * and ** (Dunnett -test); diabetic control was compared with the normal; extract and standard treated groups were compared with the diabetic control.
