PET Radiopharmaceuticals for Imaging Integrin Expression: Tracers in Clinical Studies and Recent Developments
Figure 1
[18F]Galacto-RGD PET: (A–C) patient with a soft tissue sarcoma dorsal of the right knee joint. (A) Sagittal section acquired 170 min p.i. (B) PET/CT image fusion. (C) Immunohistochemistry of a peripheral tumor section using the anti- monoclonal antibody LM609 demonstrates intense staining predominantly of tumor vasculature. (D–F) Patient with malignant melanoma and a lymph node metastasis in the right axilla. (D) Axial section acquired 140 min p.i. (E) PET/Ct image fusion. (F) Immunohistochemistry of the lymph node demonstrates intense staining predominantly of tumor cells and also blood vessels (with permission from Haubner et al. [17]).
