873010.fig.009a
(a)
873010.fig.009b
(b)
873010.fig.009c
(c)
Figure 9: Variation of (a) total solvent accessible surface area, (b) hydrophobic surface area, and (c) hydrophilic surface area over 5000 ps of MD simulation for Smo protein complexes with LY2940680, precatorine, labiatic acid, and 2,2′-[benzene-1,4-diylbis(methanediyloxybenzene-4,1-diyl)]bis(oxoacetic acid).