Research Article

A Diverse Stochastic Search Algorithm for Combination Therapeutics

Figure 2

Simulation average and theoretical expected minimum distance to optimal points for function f4a (Supplementary Table 6). The blue line represents the theoretical values for distance and the dashed blue lines represent the error margins ( ) for the analytically calculated values for Step 1 of the iteration. First figure represents the simulation with LHC equal to 40 and second figure represents the simulation LHC equal to 10. The red vertical line represents the end of Step 1, that is, Latin Hypercube Numbers, which is equal to 40th iteration; and the black vertical line represents the average value of iterations (cost of proposed algorithm) required to find one of the points with . The perpendicular cyan line represents the worst situation out of 100 different runs.
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873436.fig.002b
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