Determinants of Disability in Multiple Sclerosis: An Immunological and MRI Study

Table 1

Demographic and clinical characteristics of the study subjects.

	HClab	HC	All MS	BMS	RRMS	SPMS
Number	40	37	59	22	11	26
Mean age (SD) (years)	44.2 (10.7)	45.7 (14.4)	46.2 (9.8)	46.5 (7.2)	37.5 (9.5)	49.6 (9.9)
Men/women	12/28	15/22	21/38	9/13	5/6	7/19
Mean disease duration (SD) (years)		—	18.0 (9.6)	20.9 (4.8)	2.1 (0.7)	22.4 (7.6)
Median EDSS (range)		—	3.0 (0.0–7.5)	1.5 (0.0–3.0)	1.5 (0.0–3.0)	6.0 (4.0–7.5)

HC_lab: historical healthy controls for immunology; HC: healthy controls recruited for magnetic resonance measures; MS: multiple sclerosis; BMS: benign MS; relapsing-remitting MS; secondary progressive MS.