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BioMed Research International
Volume 2014 (2014), Article ID 890385, 7 pages
http://dx.doi.org/10.1155/2014/890385
Research Article

Early Glottic Cancer: Role of MRI in the Preoperative Staging

1Department of Experimental and Clinical Medicine-Otolaryngology Head and Neck Surgery, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy
2Department of Experimental and Clinical Medicine-Radiology, University of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy
3Department of Radiology, Pellegrini Hospital, 80135 Naples, Italy

Received 7 June 2014; Revised 12 July 2014; Accepted 23 July 2014; Published 14 August 2014

Academic Editor: Martin G. Mack

Copyright © 2014 Eugenia Allegra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Clinical staging is the most important time in management of glottic cancer in early stage (I-II). We have conducted a prospective study to evaluate if magnetic resonance imaging (MRI) is more accurate than computed tomography (CT) about tumoral extension, to exactly choose the most appropriate surgical approach, from organ preservation surgery to demolitive surgery. Materials and Methods. This prospective study was conducted on 26 male patients, with suspected laryngeal neoplasia of glottic region. The images of MRI and CT were analyzed to define the expansion of glottic lesion to anterior commissure, laryngeal cartilages, subglottic and/or supraglottic site, and paraglottic space. The results of MRI and CT were compared with each other and with the pathology report. Results. CT accuracy was 70% with low sensitivity but with high specific value. MRI showed a diagnostic accuracy in 80% of cases, with a sensitivity of 100% and high specificity. Statistical analysis showed that MRI has higher correlation than CT with the pathology report. Conclusion. Our study showed that MRI is more sensitive than CT in the preoperative staging of early glottic cancer, to select exactly the eligible patients in conservative surgery of the larynx, as supracricoid laryngectomy and cordectomy by CO2 laser.