Cerium Oxide Nanoparticles Induced Toxicity in Human Lung Cells: Role of ROS Mediated DNA Damage and Apoptosis

Figure 2

Internalization of CeO₂ NPs in A549 cells after 24 h and 48 h exposure. Cells were harvested and analyzed using flow cytometry. Increase in SSC intensity which correlates the increased granularity of cells was used as a marker for uptake of NPs. Values represent mean ± SEM of three independent experiments (^∗𝑃<0.05, ^∗∗𝑃<0.01, compared with control).