Cerium Oxide Nanoparticles Induced Toxicity in Human Lung Cells: Role of ROS Mediated DNA Damage and Apoptosis

Figure 5

Effect of CeO₂ NPs on (a, b) ROS production and (c) cellular level of glutathione (GSH) in A549 cells. (a, b) Cells were exposed and incubated with H₂DCFDA. (c) After exposure cells were collected, lysed, and incubated with reaction mixture (TCA, DTNB). Both measurements were done using microplate reader and data represents mean ± SEM of three independent experiments (^∗𝑃<0.05, ^∗∗𝑃<0.01 compared to control).

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