Improved Candidate Drug Mining for Alzheimer’s Disease

Table 2

PharmGKB-based data mining results in terms of the PharmGKB accession ID, drug class, publications, and the number of gene information of Alzheimer's disease.

No.	PharmGKB accession ID	Drug classes	Publications^*1	Gene no.^*2
1	PA164712423	Anticholinesterases	PMID: 20644562  20644562  14674789	6
2	PA164712308	Ace inhibitors, plain	PMID: 17362841	24
3	PA449515	Etanercept	PMID: 19027875	12
4	PA451262	Rivastigmine	PMID: 20644562  16323253  17082448; 20644562  15289797  17522596	2
5	PA450243	Lithium	PMID: 17082448	13
6	PA10384	Anti-inflammatory and antirheumatic products, nonsteroids	PMID: 17082448  17082448	11
7	PA449760	Glatiramer acetate	PMID: 17082448	4
8	PA133950441	Hmg coa reductase inhibitors	PMID: 17082448	39
9	PA151958596	Curcumin	PMID: 17082448	2
10	PA451898	Vitamin c	PMID: 17082448	16
11	PA451900	Vitamin e	PMID: 17082448	1
12	PA452229	Antidepressants	PMID: 17082448	43
13	PA452233	Antipsychotics	PMID: 17082448	46
14	PA449726	Galantamine	PMID: 20644562  16323253  17082448; 15853556  20644562  14674789  12177686	7
15	PA10364	Memantine	PMID: 17082448	0
16	PA451283	Rosiglitazone	PMID: 16770341	34
17	PA448031	Acetylcholine	PMID: 15695160	8
18	PA450626	Nicotine	PMID: 15695160	88
19	PA137179528	Nimesulide	PMID: 16331303  11810182	3
20	PA449394	Donepezil	PMID: 20859244  20644562  16323253; 16424819  17082448  20644562  1973817012142731	9
21	PA451576	Tacrine	PMID: 9521254  17082448  10801254; 9777427  18004213	6
22	PA448976	Choline	PMID: 8618881	122

∗1PMID: PubMed article ID number.
^*2The full gene names for each of the “drug classes” have been provided in the Supplementary file 1.