Number of Polyploid Giant Cancer Cells and Expression of EZH2 Are Associated with VM Formation and Tumor Grade in Human Ovarian Tumor
Figure 3
Human serous ovarian cancer cells generate erythrocytes. ((a) and (b)) Multiple red cell-like bodies around and within human ovarian cancer cells (black arrows, H&E ×200). (c) Many erythrocytes seen adhering to the surface of cancer cells (black arrows, H&E ×200). (d) Erythrocytes budding from PGCCs (black arrow, H&E ×200). (e) Red cell-like bodies in the cytoplasm of ovarian carcinoma cells were negative for hemoglobin-α (black arrow, IHC ×200). (f) Positive IHC staining for hemoglobin-β/γ/ε/δ in the red cell-like bodies (black arrow, IHC ×200). (g) Red cell-like bodies negative for fetal hemoglobin staining (black arrow, IHC ×200). (h) Red cell-like bodies were positive for hemoglobin- IHC staining (black arrow, ×200).
