Models of alternative possibilities for viscerovisceral cross-sensitization in the DRG neuron. (a) ATP released by a neuron innervating the inflamed uterus acts on a neighboring neuron sensitizing its responses to colonic distention. (b) The same neuron innervates the uterus and colon. Uterus inflammation directly sensitizes the neuron to colonic distention. Reproduced from Chaban, 2012, with permission [62].
