Reduction-Triggered Breakable Micelles of Amphiphilic Polyamide Amine-g-Polyethylene Glycol for Methotrexate Delivery

Table 2

Properties of the reduction-triggered breakable micelles.

Series	Micelle size (nm)^a		CMC (mg/L)^b	DLC (%)^c	DLE (%)^c
	Without drug	Drug loaded
PAA(8:2)-PEG2000	55	73	4.5	7.5	82.5
PAA(7:3)-PEG2000	37	56	20.1	6.3	69.3
PAA(6:4)-PEG2000	18	38	52.3	5.5	60.5
PAA(8:2)-PEG5000	34	42	9.4	6.9	75.9
PAA(7:3)-PEG5000	38	61	27.2	5.1	56.1
PAA(6:4)-PEG5000	70	98	44.0	2.9	31.9

aMicelle sizes were measured by DLS.
^bMeasured using pyrene as a fluorescence probe.
^cMeasured by fluorescence measurement.