Frequency of TGF-β and IFN-γ Genotype as Risk Factors for Acute Kidney Injury and Death in Intensive Care Unit Patients

Table 3

Frequency of allele (%) of TGF-β and IFN-γ polymorphisms in ICU patients according to acute kidney injury (AKI or No AKI) and control group.

Allele	AKI (146)	No AKI (82)	Control (98)	P
TGF-β
Codon 10
C/C	21 (14.3%)	11 (13.4%)	15 (15.3%)	0.30
C/T	75 (51.3%)	43 (52.4%)	50 (51.1%)
T/T	50 (34.4%)	28 (34.2%)	33 (33.6%)
Codon 25
C/C	3 (2%)	1 (1.2%)	3 (2%)	0.30
G/C	53 (36.3%)	30 (36.5%)	36 (36.7%)
G/G	90 (61.7%)	51 (62.3%)	60 (61.3%)
IFN-γ (+874 T/A)
A/A	89 (36.5%)	29 (20.9%)	41 (25%)	0.13
T/A	117 (48 %)	85 (61.2%)	97 (59.1%)
T/T	34 (13.9%)	24 (17.3%)	23 (14%)

Chi-square test and 𝑃<0.05.