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BioMed Research International
Volume 2014, Article ID 906087, 8 pages
http://dx.doi.org/10.1155/2014/906087
Review Article

Etiopathogenesis and Therapy of Epithelial Ingrowth after Descemet’s Stripping Automated Endothelial Keratoplasty

Eye Clinic, Department of Neurological and Vision Sciences, University of Brescia, Piazzale Spedale Civili 1, 25123 Brescia, Italy

Received 22 May 2014; Accepted 14 August 2014; Published 2 September 2014

Academic Editor: Leonardo Mastropasqua

Copyright © 2014 Francesco Semeraro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Ghaznawi and E. S. Chen, “Descemet's stripping automated endothelial keratoplasty: innovations in surgical technique,” Current Opinion in Ophthalmology, vol. 21, no. 4, pp. 283–287, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. G. R. J. Melles, F. A. Eggink, F. Lander et al., “A surgical technique for posterior lameliar keratoplasty,” Cornea, vol. 17, no. 6, pp. 618–626, 1998. View at Publisher · View at Google Scholar · View at Scopus
  3. M. A. Terry and P. J. Ousley, “Deep lamellar endothelial keratoplasty in the first United States patients,” Cornea, vol. 20, no. 3, pp. 239–243, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. G. R. J. Melles, R. H. J. Wijdh, and C. P. Nieuwendaal, “A technique to excise the descemet membrane from a recipient cornea (descemetorhexis),” Cornea, vol. 23, no. 3, pp. 286–288, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. M. S. Gorovoy and A. Ratanasit, “Epithelial downgrowth after descemet stripping automated endothelial keratoplasty,” Cornea, vol. 29, no. 10, pp. 1192–1194, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. F. W. Price Jr. and M. O. Price, “Descemet's stripping with endothelial keratoplasty in 50 eyes: a refractive neutral corneal transplant,” Journal of Refractive Surgery, vol. 21, no. 4, pp. 339–345, 2005. View at Google Scholar · View at Scopus
  7. F. W. Price Jr. and M. O. Price, “Descemet's stripping with endothelial keratoplasty in 200 eyes: early challenges and techniques to enhance donor adherence,” Journal of Cataract & Refractive Surgery, vol. 32, no. 3, pp. 411–418, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. R. Bansal, A. Ramasubramanian, P. Das, J. Sukhija, and A. K. Jain, “Intracorneal epithelial ingrowth after descemet stripping endothelial keratoplasty and stromal puncture,” Cornea, vol. 28, no. 3, pp. 334–337, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. P. Prasher, O. Muftuoglu, M. L. Hsiao, R. W. Bowman, R. N. Hogan, and V. V. Mootha, “Epithelial downgrowth after descemet stripping automated endothelial keratoplasty,” Cornea, vol. 28, no. 6, pp. 708–711, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. S. Vira, C. Y. Shih, N. Ragusa et al., “Textural interface opacity after descemet stripping automated endothelial keratoplasty: a report of 30 cases and possible etiology,” Cornea, vol. 32, no. 5, pp. e54–e59, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. I. E. Y. Saelens, M. C. Bartels, G. van Rij, W. N. M. Dinjens, and C. M. Mooy, “Introduction of epithelial cells in the flap-graft interface during descemet stripping automated endothelial keratoplasty,” Archives of Ophthalmology, vol. 127, no. 7, pp. 936–937, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Anshu, B. Planchard, M. O. Price, C. D. R. Pereira, and F. W. Price Jr., “A cause of reticular interface haze and its management after descemet stripping endothelial keratoplasty,” Cornea, vol. 31, no. 12, pp. 1365–1368, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. W. W. Culbertson, “Descemet stripping endothelial keratoplasty,” International Ophthalmology Clinics, vol. 46, no. 3, pp. 155–168, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. P. M. Phillips, M. A. Terry, S. C. Kaufman, and E. S. Chen, “Epithelial downgrowth after Descemet-stripping automated endothelial keratoplasty,” Journal of Cataract and Refractive Surgery, vol. 35, no. 1, pp. 193–196, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. A. D. S. Forseto, M. S. D. Santos, A. Sampaio, V. Mascaro, and W. Nosé, “Diagnosis of epithelial ingrowth after penetrating keratoplasty with confocal microscopy,” Cornea, vol. 25, no. 9, pp. 1124–1127, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Ghosh, R. Bonshek, and S. J. Morgan, “Histologically proven epithelial ingrowth in failed Descemet stripping automated endothelial keratoplasty (DSAEK) managed by repeat DSAEK,” Clinical Ophthalmology, vol. 7, pp. 1035–1040, 2013. View at Publisher · View at Google Scholar · View at Scopus
  17. S. B. Koenig and D. J. Covert, “Epithelial ingrowth after descemet-stripping automated endothelial keratoplasty,” Cornea, vol. 27, no. 6, pp. 727–729, 2008. View at Google Scholar · View at Scopus
  18. L. H. Suh, M. A. Shousha, R. U. Ventura et al., “Epithelial ingrowth after descemet stripping automated endothelial keratoplasty: description of cases and assessment with anterior segment optical coherence tomography,” Cornea, vol. 30, no. 5, pp. 528–534, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. B. M. Walker, H. B. Hindman, K. B. Ebrahimi et al., “Epithelial downgrowth following Descemet's-stripping automated endothelial keratoplasty,” Archives of Ophthalmology, vol. 126, no. 2, pp. 278–280, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. A. E. Maumenee and C. R. Shannon, “Epithelial invasion of the anterior chamber,” The American Journal of Ophthalmology, vol. 41, no. 6, pp. 929–942, 1956. View at Google Scholar · View at Scopus
  21. S. H. Chen and R. Pineda II, “Epithelial and fibrous downgrowth: mechanisms of disease,” Ophthalmology Clinics of North America, vol. 15, no. 1, pp. 41–48, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. H. V. Gimbel, E. E. Anderson Penno, J. A. Van Westenbrugge, M. Ferensowicz, and M. T. Furlong, “Incidence and management of intraoperative and early postoperative complications in 1000 consecutive laser in situ keratomileusis cases,” Ophthalmology, vol. 105, no. 10, pp. 1839–1848, 1998. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Y. Wang and R. K. Maloney, “Epithelial ingrowth after laser in situ keratomileusis,” The American Journal of Ophthalmology, vol. 129, no. 6, pp. 746–751, 2000. View at Publisher · View at Google Scholar · View at Scopus
  24. J. A. Lee, A. R. Djalilian, K. M. Riaz et al., “Clinical and histopathologic features of failed descemet stripping automated endothelial keratoplasty grafts,” Cornea, vol. 28, no. 5, pp. 530–535, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. N. Asano-Kato, I. Toda, Y. Hori-Komai, Y. Takano, and K. Tsubota, “Epithelial ingrowth after laser in situ keratomileusis: clinical features and possible mechanisms,” The American Journal of Ophthalmology, vol. 134, no. 6, pp. 801–807, 2002. View at Publisher · View at Google Scholar · View at Scopus
  26. L. H. Suh, S. H. Yoo, A. Deobhakta et al., “Complications of descemet's stripping with automated endothelial keratoplasty. Survey of 118 eyes at one institute,” Ophthalmology, vol. 115, no. 9, pp. 1517–1524, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. L. H. Suh, D. G. Dawson, L. Mutapcic et al., “Histopathological examination of failed grafts in Descemet’s stripping with automated endothelial keratoplasty,” Ophthalmology, vol. 116, no. 4, pp. 603–608, 2009. View at Publisher · View at Google Scholar · View at Scopus
  28. L. A. Sidrys and T. Demong, “Epithelial downgrowth after penetrating keratoplasty,” Canadian Journal of Ophthalmology, vol. 17, no. 1, pp. 29–31, 1982. View at Google Scholar · View at Scopus
  29. J. D. Cameron, B. A. Flaxman, and M. Yanoff, “In vitro studies of corneal wound healing: epithelial endothelial interactions,” Investigative Ophthalmology & Visual Science, vol. 13, no. 8, pp. 575–579, 1974. View at Google Scholar · View at Scopus
  30. S. C. Kaufman, D. C. Musch, M. W. Belin et al., “Confocal microscopy: a report by the American Academy of Ophthalmology,” Ophthalmology, vol. 111, no. 2, pp. 396–406, 2004. View at Publisher · View at Google Scholar · View at Scopus
  31. Y. Hara, A. Shiraishi, M. Yamaguchi, T. Uno, and Y. Ohashi, “Diagnosis and clinical course of epithelial ingrowth after Descemet-stripping automated endothelial keratoplasty followed by in vivo confocal microscopy,” Clinical and Experimental Ophthalmology, vol. 39, no. 7, pp. 710–712, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. M. J. Weiner, J. Trentacoste, D. M. Pon, and D. M. Albert, “Epithelial downgrowth: a 30-year clinicopathological review,” The British Journal of Ophthalmology, vol. 73, no. 1, pp. 6–11, 1989. View at Publisher · View at Google Scholar · View at Scopus
  33. S. Heinzelmann, D. Böhringer, P. C. Maier, and T. Reinhard, “Correlation between visual acuity and interface reflectivity measured by pentacam following DSAEK,” Acta Ophthalmologica, vol. 92, no. 1, pp. 1–4, 2014. View at Publisher · View at Google Scholar · View at Scopus
  34. R. K. Wong, D. P. Greene, D. R. Shield, C. G. Eberhart, J. J. Huang, and A. Shayegani, “5-Fluorouracil for epithelial downgrowth after descemet stripping automated endothelial keratoplasty,” Cornea, vol. 32, no. 12, pp. 1610–1612, 2013. View at Publisher · View at Google Scholar
  35. M. M. Lai and J. A. Haller, “Resolution of epithelial ingrowth in a patient treated with 5-fluorouracil,” The American Journal of Ophthalmology, vol. 133, no. 4, pp. 562–564, 2002. View at Publisher · View at Google Scholar · View at Scopus
  36. R. K. Wong, D. P. Greene, D. R. Shield, C. G. Eberhart, J. J. Huang, and A. Shayegani, “5-Fluorouracil for epithelial downgrowth after descemet stripping automated endothelial keratoplasty,” Cornea, vol. 32, no. 12, pp. 1610–1612, 2013. View at Google Scholar
  37. R. A. Latkany, F. E. Haq, and M. G. Speaker, “Advanced epithelial ingrowth 6 months after laser in situ keratomileusis,” Journal of Cataract and Refractive Surgery, vol. 30, no. 4, pp. 929–931, 2004. View at Publisher · View at Google Scholar · View at Scopus