BioMed Research International

Research Article

Successive Nonstatistical and Statistical Approaches for the Improved Antibiotic Activity of Rare Actinomycete Nonomuraea sp. JAJ18

Table 2

Plackett-Burman design and experimental response obtained for Nonomuraea sp. JAJ18.
TrialVariablesAntibiotic effect (U/mL) ± SEM
B. subtilis
1+−+−−−++120.0 ± 10.0
2++−+−−−+103.3 ± 10.4
3−++−+−−−106.7 ± 11.5
4+−++−+−−80.0 ± 10.0
5++−++−+−126.7 ± 5.78
6+++−++−+138.3 ± 2.89
7−+++−++−70.0 ± 10.0
8−−+++−++106.7 ± 5.78
9−−−+++−+86.7 ± 5.78
10+−−−+++−115.0 ± 8.67
11−+−−−+++95.0 ± 13.2
12−−−−−−−−86.7 ± 5.78