Research Article

Spider Silk as Guiding Biomaterial for Human Model Neurons

Figure 1

Human model neurons growing on steel frame wired spider silk fibers of Nephila sp. (a) Image of a female individual of the species Nephila sp. (b) Handcrafted stainless dental steel frame with cross-woven spider silk. (c) Phase contrast image of human NT2 neurons attached to fibers of the spider silk. ((d)-(e)) Neurons stained against neuronal β-type-III-tubulin (magenta) and DAPI (cyan) with neurites growing on the fibers and neurons bridging the gap and making contact to other fibers. Scale bars are 0.25 mm (b) and 25 μm ((c)–(e)).
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