Research Article

Comparison of Behaviour in Different Liquids and in Cells of Gold Nanorods and Spherical Nanoparticles Modified by Linear Polyethyleneimine and Bovine Serum Albumin

Table 1

Electron microscopic characterisation of the dispersity of GNPs in different liquids.

NPs/mediumAqueous solutionPhosphate buffer10% FBS in waterDMEM with 10% FBSConditioned DMEM

Citrate-sGNPsIndividual NPsn.d.***n.d.Agglomerates**Aggregates*
BSA-sGNPsIndividual NPsAgglomeratesIndividual NPsIndividual NPsIndividual NPs
PEI-sGNPsIndividual NPsAggregatesIndividual NPsIndividual NPsIndividual NPs
CTAB-GNRsIndividual NPsn.d.n.d.Individual NPsIndividual NPs
BSA-GNRsAggregatesAggregatesAgglomeratesIndividual NPsAgglomerates
PEI-GNRsAgglomeratesAggregatesIndividual NPs + agglomeratesIndividual NPs + agglomeratesIndividual NPs

Aggregates are clusters of NPs tightly adjacent to each other with invisible gaps between them.
**Agglomerates are loose clusters of NPs comprising more than 10 units with gaps of less than 2 nm between them, which can be seen by TEM.
***n.d.: not determined.