Research Article

biomvRhsmm: Genomic Segmentation with Hidden Semi-Markov Model

Table 4

Processing time and error estimate of the compared models.

ā€‰avg. Simulation 1Simulation 2
ā€‰avg.cpMAERMSEavg.cpMAERMSE

hsmm 0.2564512/11.165.7563.4766/6.5018.736.31
bcp 1.46298NANANANANANA
bioHMM 6.9681114/14.718.6557.376NANANA
CBS 0.1216812/11.027.4444.1785/4.9320.7627.068
CGHseg 0.2893812/9.899.0594.7837/7.0014.835.533
GLAD 0.2372510/8.2213.1286.0713/4.1522.1397.668
HaarSeg 0.0026817/15.5712.8964.98410/10.6510.1174.018
HMM 0.280087/38.9794.66680.7921/60.05144.8397.178

avg. is calculated as the mean run time of 20000 simulation iterations.
avg.cp is the median/mean number of segments estimated across 3 SNR settings.
MAE is calculated as the mean absolute error .
RMSE is the rooted mean squared error .
NA indicates that the measurement is not applicable for this algorithm. For bcp, the model output posterior means for each position that does not tend to form segments with constant mean. For bioHMM, the model cannot be run, thus no results were collected.