Current Innovations in Endoscopic Therapy for the Management of Colorectal Cancer: From Endoscopic Submucosal Dissection to Endoscopic Full-Thickness Resection

Table 2

Summary of endoscopic full-thickness resection (EFTR) procedures in an animal model.

Author	Year	Country	No. animals	Approach	Resection devices	Closure methods	Device	Procedure completed	Size of specimen (cm)	Procedure time (min)	Inoperative complication rate
Schurr et al. [53]	2001	USA	25	Endoscopy and laparotomy with endoscopic resection	Endoscopic FTRD	Pre-resection closure method	FTRD	100%	—	—	12%
Rajan et al. [54]	2001	USA	8	Endoscopic only	Endoscopic FTRD	Pre-resection closure method	FTRD	100%	Mean 3.6	Mean 30.2	50%
Raju et al. [55]	2009	USA	20	Endoscopic only	Endoscopic knife and snare	Post-resection closure method	T-tag	95%	Median 1.7	Median 50	0%
von Renteln et al. [56]	2010	Germany, Canada	8	Endoscopic only	Endoscopic snare	Pre-resection closure method	Endoloop and OTSC	100%	Mean 1.8	Mean 31.5	25%
			20		Endoscopic snare	Post-resection closure method	Twin-grasper and OTSC	45%	Mean 3.3	Mean 14.8	67%
Rieder et al. [58]	2011	Germany	2	Laparoscopically monitored endoscopic resection	Endoscopic snare	Pre-resection closure method	T-tag and OTSC	100%	Mean 2.2	Mean 33	0%
von Renteln et al. [57]	2011	Germany	8	Endoscopic only	Endoscopic snare	Pre-resection closure method	OTSC using a grasper	88%	7.6 cm^2	Median 3	25%

FTRD: full-thickness device; OTSC: Over-The-Scope.