Table of Contents Author Guidelines Submit a Manuscript
BioMed Research International
Volume 2014, Article ID 925762, 8 pages
http://dx.doi.org/10.1155/2014/925762
Research Article

Gradually Increased Training Intensity Benefits Rehabilitation Outcome after Stroke by BDNF Upregulation and Stress Suppression

1Interdisciplinary Division of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong
2Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong
3College of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China

Received 28 February 2014; Revised 14 May 2014; Accepted 21 May 2014; Published 19 June 2014

Academic Editor: Yiwen Wang

Copyright © 2014 Jing Sun et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [16 citations]

The following is the list of published articles that have cited the current article.

  • Pengyue Zhang, Jia Xianglei, Yang Hongbo, Jichuan Zhang, and Ce Xu, “Neuroprotection of Early Locomotor Exercise Poststroke: Evidence From Animal Studies,” Canadian Journal Of Neurological Sciences, vol. 42, no. 4, pp. 213–220, 2015. View at Publisher · View at Google Scholar
  • Caroline Pin-Barre, and Jérôme Laurin, “Physical Exercise as a Diagnostic, Rehabilitation, and Preventive Tool: Influence on Neuroplasticity and Motor Recovery after Stroke,” Neural Plasticity, vol. 2015, pp. 1–12, 2015. View at Publisher · View at Google Scholar
  • Senthil Kumaran, Ashu Bhasin, Padma Srivastava, Sujata Mohanty, Sivasubramaniam Vivekanandhan, Sakshi Sharma, and Rohit Bhatia, “Paracrine Mechanisms of Intravenous Bone Marrow-Derived Mononuclear Stem Cells in Chronic Ischemic Stroke,” Cerebrovascular Diseases Extra, vol. 6, no. 3, pp. 107–119, 2016. View at Publisher · View at Google Scholar
  • Yongming Zhang, Binghui Qiu, Jinbiao Wang, Yi Yao, Chunlin Wang, and Jiachuan Liu, “Effects of BDNF-Transfected BMSCs on Neural Functional Recovery and Synaptophysin Expression in Rats with Cerebral Infarction,” Molecular Neurobiology, vol. 54, no. 5, pp. 3813–3824, 2016. View at Publisher · View at Google Scholar
  • Annabelle Constans, Caroline Pin-barre, Jean-Jacques Temprado, Patrick Decherchi, and Jérôme Laurin, “Influence of Aerobic Training and Combinations of Interventions on Cognition and Neuroplasticity after Stroke,” Frontiers in Aging Neuroscience, vol. 8, 2016. View at Publisher · View at Google Scholar
  • Juliet AM Haarman, Jasper Reenalda, Jaap H Buurke, Herman van der Kooij, and Johan S Rietman, “The effect of ‘device-in-charge’ versus ‘patient-in-charge’ support during robotic gait training on walking ability and balance in chronic stroke survivors: A systematic review,” Journal of Rehabilitation and Assistive Technologies Engineering, vol. 3, pp. 205566831667678, 2016. View at Publisher · View at Google Scholar
  • Nicola Lamberti, Sofia Straudi, Anna Maria Malagoni, Matteo Argirò, Michele Felisatti, Eleonora Nardini, Christel Zambon, Nino Basaglia, and Fabio Manfredini, “Effects of low-intensity endurance and resistance training on mobility in chronic stroke survivors: A pilot randomized controlled study,” European Journal of Physical and Rehabilitation Medicine, vol. 53, no. 2, pp. 228–239, 2017. View at Publisher · View at Google Scholar
  • Yihao Deng, Liqiang Yang, Jie Zhang, and Pengyue Zhang, “The Effects of Early Exercise on Motor, Sense, and Memory Recovery in Rats with Stroke,” American Journal of Physical Medicine and Rehabilitation, vol. 96, no. 3, pp. e36–e43, 2017. View at Publisher · View at Google Scholar
  • Sadegh Abbasian, and Mahsa Rastegar MM, “Is the Intensity or Duration of Treadmill Training Important for Stroke Patients? A Meta-Analysis,” Journal of Stroke and Cerebrovascular Diseases, 2017. View at Publisher · View at Google Scholar
  • E. V. Kostenko, “Influence chronopharmacology therapy methionine (melaxen) on the dynamics of sleep disturbance, cognitive and emotional disorders, brain-derived neurotrophic factor (BDNF) in patients with cerebral stroke in the early and late recovery periods,” Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, vol. 117, no. 3, pp. 56, 2017. View at Publisher · View at Google Scholar
  • Christopher P. Mackay, Suzanne S. Kuys, and Sandra G. Brauer, “The Effect of Aerobic Exercise on Brain-Derived Neurotrophic Factor in People with Neurological Disorders: A Systematic Review and Meta-Analysis,” Neural Plasticity, vol. 2017, pp. 1–9, 2017. View at Publisher · View at Google Scholar
  • Carolina C. Alcantara, Luisa F. García-Salazar, Marcela A. Silva-Couto, Gabriela L. Santos, Darcy S. Reisman, and Thiago L. Russo, “Post-stroke BDNF Concentration Changes Following Physical Exercise: A Systematic Review,” Frontiers in Neurology, vol. 9, 2018. View at Publisher · View at Google Scholar
  • Ying Xing, Si-Dong Yang, Fang Dong, Man-Man Wang, Ya-Shuo Feng, and Feng Zhang, “The beneficial role of early exercise training following stroke and possible mechanisms,” Life Sciences, vol. 198, pp. 32–37, 2018. View at Publisher · View at Google Scholar
  • Min Sun Kim, Ho Koo, Myung Ae Choi, Se Jin Moon, Seung Bum Yang, and Jae-Hyo Kim, “ Combination of Transcranial Electro-Acupuncture and Fermented Scutellaria baicalensis Ameliorates Motor Recovery and Cortical Neural Excitability Following Focal Stroke in Rats ,” Korean Journal of Acupuncture, vol. 35, no. 4, pp. 187–202, 2018. View at Publisher · View at Google Scholar
  • E. I. Gusev, M. Yu. Martynov, E. V. Kostenko, L. V. Petrova, and S. N. Bobyreva, “The efficacy of semax in the tretament of patients at different stages of ischemic stroke,” Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, vol. 118, no. 3, pp. 61, 2018. View at Publisher · View at Google Scholar
  • Li-Mei Cao, Zhi-Qiang Dong, Qiang Li, and Xu Chen, “Treadmill training improves neurological deficits and suppresses neuronal apoptosis in cerebral ischemic stroke rats,” Neural Regeneration Research, vol. 14, no. 8, pp. 1387, 2019. View at Publisher · View at Google Scholar