BioMed Research International

Research Article

Probiotic Potential of Lactobacillus Strains with Antimicrobial Activity against Some Human Pathogenic Strains

Table 7

Antagonistic activity of Lactobacillus strains against test pathogens.

Lactobacillus strain

Inhibition zone (from outer edge of Lactobacillus colony to outer edge of clear zone) (mm)¹

Candida albicans
(ATCC 44831)

Propionibacterium acnes
(ATCC 6919)

Shigella sonnei
(ATCC 25931)

Helicobacter pylori
(ATCC 43579)

Enterobacter cloacae

Vibrio parahaemolyticus

Listeria monocytogenes

E. coli
(ATCC 29181)

Enterococcus faecium
(ATCC 51558)

Staphylococcus epidermidis
(ATCC12228)

Staphylococcus aureus
(S244)

Klebsiella pneumoniae
(K36)

L. casei Shirota*

13.8^bc

11.2^c

13.5^d

14.2^e

18.7^d

6.5^e

14.0^f

11.7^c

11.8^b

18.3^b

14.0^d

7.8^d

L. acidophilus HM1

9.7^d

3.3^e

6.3^e

16.2^d

7.2^e

7.0^e

13.7^f

11.8^c

11.2^bc

12.0^c

6.7^e

5.0^e

L. fermentum HM2

13.5^c

11.2^c

14.5^cd

18.7^c

20.8^c

11.7^cd

24.0^b

14.7^ab

13.7^a

22.5^a

14.5^d

10.5^b

L. fermentum HM3

15.2^a

11.2^c

14.5^cd

19.3^c

20.8^c

11.7^cd

25.7^a

14.5^ab

14.2^a

23.3^a

14.5^d

10.5^b

L. buchneri FG1

15.0^ab

4.3^de

15.0^bc

15.5^d

22.5^ab

12.3^bc

22.3^cd

12.0^c

11.2^bc

23.3^a

17.0^c

11.0^b

L. buchneri FD1

15.0^ab

5.2^d

14.3^cd

15.3^d

22.5^ab

12.2^cd

23.8^bc

11.3^c

10.7^c

24.2^a

17.5^c

11.2^b

L. buchneri FD2

14.7^ab

4.3^de

13.7^d

16.3^d

23.2^a

11.2^c

21.8^d

11.5^c

10.5^c

24.2^a

17.2^c

12.7^a

L. casei BF1**

15.0^ab

16.5^a

16.0^ab

20.7^b

21.5^bc

14.5^a

20.7^de

14.8^a

11.8^b

23.7^a

20.2^a

9.5^c

L. casei BF2**

15.5^a

16.5^a

16.7^a

22.2^a

22.3^abc

13.3^b

19.7^e

14.0^ab

11.7^b

23.0^a

19.2^ab

8.8^c

L. casei BF3**

15.0^ab

14.8^b

16.5^a

22.0^a

22.2^abc

14.5^a

20.8^de

13.8^b

11.3^bc

23.0^a

18.8^b

9.0^c

SEM

0.19

0.52

0.32

0.47

0.59

0.30

0.42

0.17

0.14

0.39

0.40

0.25

Values are means of two independent experiments, each in triplicate.
Means with different superscripts within a column are significantly different ().
Reference strain.
These strains that showed higher antagonistic activities than other strains against most of tested pathogenic strains, also produced higher amounts of lactic acid (Table 9).