Probiotic Potential of Lactobacillus Strains with Antimicrobial Activity against Some Human Pathogenic Strains

Table 9

Organic acid production of Lactobacillus strains.

Lactobacillus strain	Non-volatile fatty acids (mM)^1			Volatile fatty acids (mM)^1
	Lactic acid	Succinic acid	Acetic acid	Propionic acid	Isobutyric acid	Butyric acid	Isovaleric acid	Valeric acid	Caproic acid
L. casei Shirota*	185.78 ± 10.85^f	1.41 ± 0.13^d	68.08 ± 2.63^c	ND	ND	ND	ND	ND	ND
L. acidophilus HM1	143.65 ± 5.38^g	25.18 ± 0.40^b	71.54 ± 3.09^c	0.32 ± 0.01	ND	ND	ND	ND	ND
L. fermentum HM2	227.07 ± 12.75^c	23.97 ± 0.41^c	130.14 ± 7.89^a	ND	ND	ND	ND	ND	ND
L. fermentum HM3	209.80 ± 4.52^de	24.00 ± 0.56^c	125.71 ± 5.35^a	ND	ND	ND	ND	ND	0.39 ± 0.01
L. buchneri FG1	196.08 ± 11.36^ef	26.33 ± 0.83^a	124.16 ± 7.38^a	ND	ND	ND	0.22 ± 0.00	ND	ND
L. buchneri FD1	205.70 ± 3.65^de	1.78 ± 0.15^d	82.46 ± 4.49^b	0.15 ± 0.03	ND	ND	0.29 ± 0.00	ND	ND
L. buchneri FD2	218.70 ± 3.65^cd	2.08 ± 0.57^d	92.85 ± 5.29^b	0.33 ± 0.02	0.26 ± 0.05	0.38 ± 0.03	0.25 ± 0.05	0.16 ± 0.03	0.16 ± 0.03
L. casei BF1**	356.95 ± 5.14^a	1.77 ± 0.17^d	70.76 ± 11.19^c	ND	0.15 ± 0.01	ND	0.25 ± 0.04	0.16 ± 0.01	0.64 ± 0.02
L. casei BF2**	353.15 ± 13.23^a	1.73 ± 0.17^d	81.18 ± 13.88^bc	ND	ND	ND	0.27 ± 0.01	0.17 ± 0.02	ND
L. casei BF3**	310.97 ± 3.50^b	1.71 ± 0.28^d	70.89 ± 4.90^c	0.35 ± 0.03	0.22 ± 0.01	0.38 ± 0.02	0.21 ± 0.02	0.34 ± 0.00	0.12 ± 0.01

1Values are means ± SD of two independent experiments, each in triplicate.
a--fMeans within a column with different superscripts are significantly different (𝑃<0.05).
ND: not detected.
*Reference strain.
**These strains, which produced higher amounts of lactic acid than other strains, generally also exhibited higher antagonistic activities against most of the tested pathogenic strains (Table 7).